The COPS8 Antibody (N-term) from MyBioSource.com is a Rabbit Polyclonal antibody to COP9 complex homolog subunit 8, CSN8, and SGN8. This antibody recognizes Human antigen. The COPS8 Antibody (N-term) has been validated for the following applications: ELISA, and Western Blot.
Description
The protein encoded by this gene is one of the eight
subunits of COP9 signalosome, a highly conserved protein complex
that functions as an important regulator in multiple signaling
pathways. The structure and function of COP9 signalosome is similar
to that of the 19S regulatory particle of 26S proteasome. COP9
signalosome has been shown to interact with SCF-type E3 ubiquitin
ligases and act as a positive regulator of E3 ubiquitin ligases.
Alternatively spliced transcript variants encoding distinct
isoforms have been observed